Product Name |
Diacerein |
CAS |
13739-02-1 |
molecular formula |
C19H12O8 |
molecular weight
|
368.29 |
melting point
|
217-2180C |
form |
powder |
Diacreine, also known as diacetyldihydroanthracene carboxylic acid, 1, 8-diacetyl-3-carboxyanthraquinone, daceridine, and ambitin, is a new interleukin (IL) -1 inhibitor, chemical name is diacetylrhein, belongs to the anthraquinone compound, this product can induce chondrogenesis, has analgesic, anti-inflammatory and antipyretic effects, and can also significantly improve the joint function of osteoarthritis patients. Delay the course of the disease, reduce pain, improve the quality of life of patients, with good safety, clinical mainly used in the treatment of osteoarthritis (OA) and play an antibacterial role. Solubility: soluble in dimethyl sulfoxide and dimethyl acetamide; Insoluble in water, methanol, chloroform.
Diacetorein and its active metabolite Rhubarb (rhein) reduce IL-1β production and activity by inhibiting IL-1 converting enzyme. The mechanism of action includes:
1, inhibit IL-1 synthesis in synovial tissue.
2, inhibit the expression of IL-1 receptor in chondrocytes.
3, inhibit IL-1 activity.
4. Inhibit the production of metalloproteinases and peroxides such as collagenase and stromatolysin.
5, promote the synthesis of collagen and amino polysaccharide.
6, inhibit the chemotaxis of leukocytes and stabilize lysosomes.
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1. Do you accept sample orders?
We accept sample orders. We will make samples before mass production, and we will start mass production after the samples are passed. 100% inspection during production, random inspection before packaging.
2.What are your payment terms ?
We usually accept T/T, Western Union, USDT.
3. What is your minimum order quantity?
Our minimum order quantity is 1 kg. But usually we accept a smaller quantity, such as 100g, on condition that 100% of the sample fee is paid.
4. Do you provide product reports?
Yes. We will give you the product analysis report before shipment.
5.When will it be delivered?
We will arrange the delivery of the order after confirming the receipt.